Charles River Laboratories International, Inc. provides drug discovery, non-clinical development, and safety testing services in the United States, Europe, Canada, the Asia Pacific, and internationally. The Research Models and Services segment produces and sells rodents, and purpose-bred rats and mice for use by researchers. This segment also provides a range of services to assist its clients in supporting the use of research models in research and screening pre-clinical drug candidates, including genetically engineered models and services, insourcing solutions, and research animal diagnostic services; and engages in development and production of cell therapies. The Discovery and Safety Assessment segment offers in vitro and in vivo discovery services for the discovery, development, and safety testing of novel drugs, molecule compounds, oligonucleotides, and biotherapeutics, and antibodies through delivery of preclinical drug and therapeutic candidates ready for safety assessment; safety assessment services, such as toxicology, pathology, safety pharmacology, bioanalysis, drug metabolism, and pharmacokinetics services; and vivarium space services. The Manufacturing Solutions segment provides in vitro methods for conventional and rapid quality control testing of sterile and non-sterile pharmaceuticals and consumer products; offers specialized testing of biologics that are outsourced by pharmaceutical and biotechnology companies; and contract development and manufacturing products and services. The company has strategic collaborations with Parker Institute for Cancer Immunotherapy and Children's Hospital Los Angeles across its contract development and manufacturing organization. Additionally, it has a strategic alliance with Francis Crick Institute (Crick), Inc. for the development of Antibody-Drug Conjugate (ADC) drug discovery and development. Charles River Laboratories International, Inc. was founded in 1947 and is headquartered in Wilmington, Massachusetts.
5-year financial trends. Figures in USD millions.
Latest fiscal year: 2025
Year-by-year revenue, profitability, and cash flow (USD millions, last 10 years)
| Year | Revenue | EBITDA | Net Profit | FCF | ROE | Rev Growth 1Y | NP Growth 1Y |
|---|---|---|---|---|---|---|---|
| 2025 | $4.0B | $411M | $-144M | $518M | -4.6% | -0.9% | -1501.7% |
| 2024 | $4.0B | $581M | $10M | $502M | 0.3% | -1.9% | -97.8% |
| 2023 | $4.1B | $1.0B | $475M | $365M | 13.2% | 3.9% | -2.4% |
| 2022 | $4.0B | $986M | $486M | $295M | 16.3% | - |
Income statement, balance sheet, and cash flow as reported
Consolidated Figures in USD Millions.
| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Total Revenue | - | 3,976.06 | 4,129.41 | 4,049.99 | 4,015.38 |
| Operating Revenue | - | 3,976.06 | 4,129.41 | 4,049.99 | 4,015.38 |
| Cost Of Revenue | - | 2,513.41 | 2,626.85 | 2,718.17 | 2,692.11 |
| Gross Profit | - | 1,462.65 | 1,502.56 | 1,331.82 | 1,323.28 |
| Operating Expense | - | 811.68 | 885.30 | 889.47 | 922.14 |
| Selling General And Administration | - | 665.10 | 747.86 | 751 | 743.07 |
| Total Expenses | - | 3,325.08 | 3,512.15 | 3,607.64 | 3,614.25 |
| Operating Income | - | 650.98 | 617.26 | 442.35 | 401.14 |
| Total Operating Income As Reported | - | 650.98 | 617.26 | 227.35 | 25.16 |
| EBITDA | - | 986.15 | 1,032.12 | 581.14 | 410.84 |
| Normalized EBITDA | - | 986.15 | 1,032.12 | 796.14 | 786.81 |
| EBIT | - | 682.28 | 717.99 | 219.40 | 7.53 |
| Interest Income | - | 0.78 | 5.20 | 8.57 | 4.94 |
| Interest Expense | - | 59.29 | 136.71 | 126.29 | 107.03 |
| Net Interest Income | - | -58.51 | -131.51 | -117.71 | -102.09 |
| Other Non Operating Income Expenses | - | 30.52 | 95.54 | -16.52 | -22.58 |
| Other Income Expense | - | 30.52 | 95.54 | -231.52 | -398.55 |
| Interest Income Non Operating | - | 0.78 | 5.20 | 8.57 | 4.94 |
| Interest Expense Non Operating | - | 59.29 | 136.71 | 126.29 | 107.03 |
| Net Non Operating Interest Income Expense | - | -58.51 | -131.51 | -117.71 | -102.09 |
| Pretax Income | - | 622.99 | 581.28 | 93.11 | -99.50 |
| Tax Provision | - | 130.38 | 100.91 | 67.82 | 42.66 |
| Tax Rate For Calcs | - | 0 | 0 | 0 | 0 |
| Tax Effect Of Unusual Items | - | 0 | 0 | -45.15 | -78.95 |
| Net Income Continuous Operations | - | 492.61 | 480.37 | 25.29 | -142.16 |
| Net Income From Continuing And Discontinued Operation | - | 486.23 | 474.62 | 10.30 | -144.34 |
| Net Income From Continuing Operation Net Minority Interest | - | 486.23 | 474.62 | 10.30 | -144.34 |
| Net Income | - | 486.23 | 474.62 | 10.30 | -144.34 |
| Net Income Common Stockholders | - | 486.23 | 474.62 | 10.30 | -144.34 |
| Net Income Including Noncontrolling Interests | - | 492.61 | 480.37 | 25.29 | -142.16 |
| Normalized Income | - | 486.23 | 474.62 | 180.15 | 152.68 |
| Diluted NI Availto Com Stockholders | - | 486.23 | 474.62 | 10.30 | -144.34 |
| Basic Average Shares | - | 50.81 | 51.23 | 51.38 | 49.56 |
| Diluted Average Shares | - | 51.30 | 51.45 | 51.63 | 49.56 |
| Reconciled Depreciation | - | 303.87 | 314.12 | 361.74 | 403.31 |
| Reconciled Cost Of Revenue | - | 2,356.12 | 2,450.17 | 2,494.90 | 2,467.86 |
| Total Unusual Items | - | 0 | 0 | -215 | -375.97 |
| Total Unusual Items Excluding Goodwill | - | 0 | 0 | -215 | -375.97 |
| Minority Interests | - | -6.38 | -5.75 | -14.99 | -2.17 |
| Special Income Charges | - | 0 | 0 | -215 | -375.97 |
| Impairment Of Capital Assets | - | 0 | 0 | 215 | 375.97 |
| Depreciation Amortization Depletion Income Statement | - | 146.58 | 137.44 | 138.47 | 179.07 |
| Depreciation And Amortization In Income Statement | - | 146.58 | 137.44 | 138.47 | 179.07 |
| Otherunder Preferred Stock Dividend | - | 0 | 0 | 11.91 | - |
| Amortization | - | 146.58 | 137.44 | 138.47 | 179.07 |
| Amortization Of Intangibles Income Statement | - | 146.58 | 137.44 | 138.47 | 179.07 |
Healthcare sector peers, ranked by market cap
| Company | Ticker | Market Cap | P/E | P/B | ROE | EV/EBITDA |
|---|---|---|---|---|---|---|
| Charles River Laboratories International, Inc.this co. | CRL | $8.9B | - | 2.83 | -4.6% | 27.52 |
| Molina Healthcare, Inc. | MOH | $10.0B | 21.28 | 2.47 | 11.6% | - |
| Baxter International Inc. | BAX | $10.0B | -10.44 | 1.63 | -15.6% | 23.25 |
| Krystal Biotech, Inc. | KRYS | $9.1B | 44.30 | 7.44 | 16.8% | 51.16 |
| Henry Schein, Inc. |
| - |
| 2021 | - | - | - | - | - | - | - |
| HSIC |
| $8.7B |
| 21.84 |
| 2.68 |
| 12.3% |
| 12.42 |
| Bio-Techne Corporation | TECH | $8.3B | 113.50 | 4.34 | 3.8% | 39.69 |
| Corcept Therapeutics Incorporated | CORT | $8.0B | 80.68 | 12.41 | 15.4% | 66.11 |
| Alkermes plc | ALKS | $7.2B | 29.92 | 3.97 | 13.3% | 20.89 |
| Glaukos Corporation | GKOS | $7.1B | -38.08 | 10.89 | -28.6% | -49.02 |
| Peer Median | - | 25.88 | 4.16 | 11.9% | 23.25 | |