Lantheus Holdings, Inc. develops, manufactures, and commercializes diagnostic and therapeutic products that assist clinicians in diagnosis and treatment of heart, cancer, and other diseases worldwide. The company offers DEFINITY, an injectable ultrasound enhancing agent used in echocardiography exams; TechneLite, a technetium generator for nuclear medicine procedures; Xenon-133, a radiopharmaceutical gas to assess pulmonary function; Neurolite, an injectable imaging agent to identify the area within the brain where blood flow has been blocked or reduced due to stroke; Cardiolite, an injectable Tc-99m-labeled imaging agent to assess blood flow to the muscle of the heart; and PYLARIFY, an F 18-labelled PSMA-targeted PET imaging agent used for imaging of PSMA positive-lesions in men with prostate cancer. It also provides Automated Bone Scan Index that calculates the disease burden of prostate cancer by detecting and classifying bone scan tracer uptakes as metastatic or benign lesions using an artificial neural network; RELISTOR for opioid-induced constipation; and aPROMISE, an artificial intelligence medical device software; PYLARIFY AI, an medical device software to perform quantitative assessment of PSMA PET/CT images in prostate cancer; and flurpiridaz used to assess blood flow to the heart. In addition, it develops PNT2002, a radiopharmaceutical therapy to treat mCRPC; PNT2003, an SSTR therapy to patients with SSTR-positive neuroendocrine tumors; MK-6240, a F 18-labeled PET imaging agent for Tau tangles in Alzheimer's disease; LNTH-2401, a novel radiodiagnostic targeting the gastrin-releasing peptide receptor; LNTH-2402; LNTH-2403; LNTH-2404; LNTH-250; LNTH-2515; and LNTH-1363S, an fibroblast activation protein, alpha, copper-64 labeled PET imaging agent. It has collaboration agreements with GE Healthcare; Curium Pharma; POINT; Regeneron; and Ratio Therapeutics LLC. The company was founded in 1956 and is based in Bedford, Massachusetts.
5-year financial trends. Figures in USD millions.
Latest fiscal year: 2025
Year-by-year revenue, profitability, and cash flow (USD millions, last 10 years)
| Year | Revenue | EBITDA | Net Profit | FCF | ROE | Rev Growth 1Y | NP Growth 1Y |
|---|---|---|---|---|---|---|---|
| 2025 | $1.5B | $404M | $234M | $349M | 21.4% | 0.5% | -25.2% |
| 2024 | $1.5B | $515M | $312M | $465M | 28.7% | 18.3% | -4.4% |
| 2023 | $1.3B | $491M | $327M | $259M | 40.0% | 38.6% | 1063.9% |
| 2022 | $935M | $82M | $28M | $263M | 6.3% | - | - |
Income statement, balance sheet, and cash flow as reported
Consolidated Figures in USD Millions.
| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Total Revenue | 935.06 | 1,296.43 | 1,533.91 | 1,541.61 |
| Cost Of Revenue | 353.36 | 586.89 | 545.62 | 599.66 |
| Gross Profit | 581.70 | 709.54 | 988.29 | 941.95 |
| Operating Expense | 545.51 | 344.90 | 539.73 | 626.39 |
| Operating Income | 36.20 | 364.64 | 448.56 | 315.56 |
| EBITDA | 81.83 | 491 | 515.27 | 403.64 |
| EBIT | 33.90 | 430.96 | 450.65 | 333.54 |
| Pretax Income | 26.72 | 410.94 | 430.98 | 313.79 |
| Tax Provision | -1.35 | 84.28 | 118.53 | 80.23 |
| Net Income | 28.07 | 326.66 | 312.44 | 233.56 |
| Net Income Common Stockholders | 28.07 | 326.66 | 312.44 | 233.56 |
| Total Expenses | 898.87 | 931.79 | 1,085.35 | 1,226.05 |
| Interest Expense | 7.18 | 20.02 | 19.67 | 19.75 |
| Interest Income | 2.61 | 19.64 | 36.84 | 23.39 |
| Research And Development | 311.68 | 77.71 | 168.10 | 177.31 |
| Selling General And Administration | 233.83 | 267.19 | 371.63 | 453.81 |
| Normalized EBITDA | 86.74 | 444.18 | 551.05 | 409 |
| Normalized Income | 31.94 | 289.44 | 338.38 | 237.54 |
| Basic EPS | 0.41 | 4.79 | 4.52 | 3.46 |
| Diluted EPS | 0.40 | 4.65 | 4.36 | 3.41 |
| Tax Effect Of Unusual Items | -1.03 | 9.60 | -9.84 | -1.37 |
| Tax Rate For Calcs | 0.21 | 0.20 | 0.28 | 0.26 |
| Total Unusual Items | -4.90 | 46.83 | -35.78 | -5.36 |
| Total Unusual Items Excluding Goodwill | -4.90 | 46.83 | -35.78 | -5.36 |
| Net Income From Continuing Operation Net Minority Interest | 28.07 | 326.66 | 312.44 | 233.56 |
| Reconciled Depreciation | 47.93 | 60.04 | 64.62 | 70.10 |
| Reconciled Cost Of Revenue | 353.36 | 586.89 | 545.62 | 599.66 |
| Net Interest Income | -4.57 | -0.38 | 17.17 | 3.64 |
| Net Income From Continuing And Discontinued Operation | 28.07 | 326.66 | 312.44 | 233.56 |
| Total Operating Income As Reported | 36.20 | 364.64 | 456.98 | 310.83 |
| Diluted Average Shares | 70.67 | 70.24 | 71.65 | 68.44 |
| Basic Average Shares | 68.49 | 68.27 | 69.20 | 67.49 |
| Diluted NI Availto Com Stockholders | 28.07 | 326.66 | 312.44 | 233.56 |
| Net Income Including Noncontrolling Interests | 28.07 | 326.66 | 312.44 | 233.56 |
| Net Income Continuous Operations | 28.07 | 326.66 | 312.44 | 233.56 |
| Other Income Expense | -4.90 | 46.68 | -34.76 | -5.41 |
| Other Non Operating Income Expenses | 0 | -0.14 | 1.02 | -0.05 |
| Special Income Charges | -4.65 | 46.85 | 8.52 | 4.27 |
| Gain On Sale Of Ppe | 0 | 51.79 | 8.41 | 5 |
| Other Special Charges | 4.65 | 4.94 | -0.11 | 0.73 |
| Gain On Sale Of Security | -0.26 | -0.02 | -44.30 | -9.62 |
| Net Non Operating Interest Income Expense | -4.57 | -0.38 | 17.17 | 3.64 |
| Interest Expense Non Operating | 7.18 | 20.02 | 19.67 | 19.75 |
| Interest Income Non Operating | 2.61 | 19.64 | 36.84 | 23.39 |
| Other Operating Expenses | 0 | 0 | 0 | -4.73 |
| Selling And Marketing Expense | 100.24 | 141.74 | 177.94 | 178.69 |
| General And Administrative Expense | 133.58 | 125.46 | 193.69 | 275.12 |
| Other Gand A | 133.58 | 125.46 | 193.69 | 275.12 |
| Operating Revenue | 935.06 | 1,296.43 | 1,533.91 | 1,541.61 |
Healthcare sector peers, ranked by market cap
| Company | Ticker | Market Cap | P/E | P/B | ROE | EV/EBITDA |
|---|---|---|---|---|---|---|
| Lantheus Holdings, Inc.this co. | LNTH | $5.3B | 23.80β discount | 4.81 | 21.4% | 14.41 |
| CG Oncology, Inc. | CGON | $5.7B | - | 6.94 | -21.4% | -24.99 |
| Rhythm Pharmaceuticals, Inc. | RYTM | $5.6B | - | 39.69 | -72.8% | -28.64 |
| Scholar Rock Holding Corporation | SRRK | $5.5B | - | 20.46 | -154.0% | -13.21 |
| Immunovant, Inc. | IMVT | $5.5B |
| - |
| 5.56 |
| -58.5% |
| -9.23 |
| Oscar Health, Inc. | OSCR | $5.4B | - | 5.45 | -45.2% | -5.02 |
| Xenon Pharmaceuticals Inc. | XENE | $5.4B | - | 7.67 | -59.5% | -11.06 |
| PACS Group, Inc. | PACS | $5.2B | 27.38 | 5.53 | 20.1% | 23.70 |
| CRISPR Therapeutics AG | CRSP | $4.9B | - | 2.53 | -30.3% | -5.64 |
| Peer Median | - | 27.38 | 6.25 | -51.8% | -10.14 | |