AnaptysBio, Inc., a clinical-stage biotechnology company, focuses in delivering immunology therapeutics for autoimmune and inflammatory diseases in the United States. The company's products include Rosnilimab, a selective pathogenic T cell deplete which completed a Phase 2b trial for the treatment of moderate-to-severe rheumatoid arthritis; ANB033, a CD122 antagonist, which is in a Phase 1b trial for celiac disease and eosinophilic esophagitis; ANB101, a BDCA2 modulator antibody which is in Phase 1a trial that specifically targets plasmacytoid dendritic cells and inhibits interferon secretion and modulates antigen presentation; dostarlimab, a PD-1 antagonist for various solid tumor indications; and Imsidolimab, an antibody that inhibits the interleukin-36 receptor, which is in the Phase 3 development for the treatment of generalized pustular psoriasis. It focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations. It has collaborations agreement with GSK and Vanda. The company was formerly known as Anaptys Biosciences, Inc. and changed its name to AnaptysBio, Inc. in July 2006. AnaptysBio, Inc. was incorporated in 2005 and is based in San Diego, California.
5-year financial trends. Figures in USD millions.
Latest fiscal year: 2025
Year-by-year revenue, profitability, and cash flow (USD millions, last 10 years)
| Year | Revenue | EBITDA | Net Profit | FCF | ROE | Rev Growth 1Y | NP Growth 1Y |
|---|---|---|---|---|---|---|---|
| 2025 | $235M | $69M | $-13M | $20M | -35.6% | 157.0% | - |
| 2024 | $91M | $-93M | $-145M | $-136M | -204.9% | 432.0% | - |
| 2023 | $17M | $-143M | $-164M | $-122M | -185.7% | 66.8% | - |
| 2022 | $10M | $-105M | $-129M | $-74M | -49.1% | - | - |
Income statement, balance sheet, and cash flow as reported
Consolidated Figures in USD Millions.
| Metric | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|
| Total Revenue | 10.29 | 17.16 | 91.28 | 234.60 |
| Operating Expense | 125.44 | 174.23 | 206.23 | 186.71 |
| Operating Income | -115.15 | -157.07 | -114.95 | 47.90 |
| EBITDA | -105.26 | -143.16 | -92.74 | 69.25 |
| EBIT | -107.59 | -145.54 | -95.14 | 66.83 |
| Pretax Income | -128.70 | -163.62 | -145.23 | -13.07 |
| Tax Provision | 0.02 | 0 | 0 | 0.16 |
| Net Income | -128.72 | -163.62 | -145.23 | -13.23 |
| Net Income Common Stockholders | -128.72 | -163.62 | -145.23 | -13.23 |
| Total Expenses | 125.44 | 174.23 | 206.23 | 186.71 |
| Interest Expense | 21.11 | 18.08 | 50.09 | 79.89 |
| Interest Income | 7.55 | 18.87 | 19.79 | 13.50 |
| Research And Development | 88.80 | 132.28 | 163.84 | 135.97 |
| Selling General And Administration | 36.64 | 41.95 | 42.39 | 50.74 |
| Normalized EBITDA | -105.26 | -135.82 | -92.74 | 69.25 |
| Normalized Income | -128.72 | -156.28 | -145.23 | -13.23 |
| Basic EPS | -4.57 | -6.08 | -5.12 | -0.46 |
| Diluted EPS | -4.57 | -6.08 | -5.12 | -0.46 |
| Tax Effect Of Unusual Items | 0 | 0 | 0 | 0 |
| Tax Rate For Calcs | 0.21 | 0 | 0.21 | 0.21 |
| Total Unusual Items | 0 | -7.34 | 0 | 0 |
| Total Unusual Items Excluding Goodwill | 0 | -7.34 | 0 | 0 |
| Net Income From Continuing Operation Net Minority Interest | -128.72 | -163.62 | -145.23 | -13.23 |
| Reconciled Depreciation | 2.33 | 2.38 | 2.40 | 2.42 |
| Net Interest Income | -13.56 | 0.79 | -30.29 | -66.39 |
| Net Income From Continuing And Discontinued Operation | -128.72 | -163.62 | -145.23 | -13.23 |
| Total Operating Income As Reported | -115.15 | -164.41 | -114.95 | 47.90 |
| Diluted Average Shares | 28.16 | 26.92 | 28.38 | 28.76 |
| Basic Average Shares | 28.16 | 26.92 | 28.38 | 28.76 |
| Diluted NI Availto Com Stockholders | -128.72 | -163.62 | -145.23 | -13.23 |
| Net Income Including Noncontrolling Interests | -128.72 | -163.62 | -145.23 | -13.23 |
| Net Income Continuous Operations | -128.72 | -163.62 | -145.23 | -13.23 |
| Other Income Expense | 0.01 | -7.34 | 0.01 | 5.43 |
| Other Non Operating Income Expenses | 0.01 | 0 | 0.01 | 5.43 |
| Special Income Charges | 0 | -7.34 | 0 | 0 |
| Other Special Charges | 0 | 7.34 | 0 | 0 |
| Restructuring And Mergern Acquisition | 0 | 7.34 | 0 | 0 |
| Net Non Operating Interest Income Expense | -13.56 | 0.79 | -30.29 | -66.39 |
| Interest Expense Non Operating | 21.11 | 18.08 | 50.09 | 79.89 |
| Interest Income Non Operating | 7.55 | 18.87 | 19.79 | 13.50 |
| General And Administrative Expense | 36.64 | 41.95 | 42.39 | 50.74 |
| Other Gand A | 36.64 | 41.95 | 42.39 | 50.74 |
| Operating Revenue | 10.29 | 17.16 | 91.28 | 234.60 |
Healthcare sector peers, ranked by market cap
| Company | Ticker | Market Cap | P/E | P/B | ROE | EV/EBITDA |
|---|---|---|---|---|---|---|
| AnaptysBio, Inc.this co. | ANAB | $1.8B | - | 46.94 | -35.6% | 36.55 |
| GeneDx Holdings Corp. | WGS | $1.8B | - | 5.97 | -6.8% | 141.02 |
| Inhibrx Biosciences, Inc. | INBX | $1.8B | - | 227.77 | -1752.2% | -13.63 |
| Syndax Pharmaceuticals, Inc. | SNDX | $1.8B | - | 27.92 | -441.6% | -6.40 |
| Surgery Partners, Inc. | SGRY | $1.8B | - |
| 1.04 |
| -2.2% |
| 11.28 |
| Taysha Gene Therapies, Inc. | TSHA | $1.8B | - | 7.24 | -44.1% | -14.19 |
| Sonida Senior Living, Inc. | SNDA | $1.8B | - | -37500.00 | -125.8% | 57.41 |
| Harmony Biosciences Holdings, Inc. | HRMY | $1.8B | 11.23 | 2.05 | 18.2% | 4.68 |
| Palvella Therapeutics, Inc. | PVLA | $1.8B | - | 54.18 | -149.1% | - |
| Peer Median | - | 11.23 | 6.60 | -85.0% | 4.68 | |