AnaptysBio, Inc., a clinical-stage biotechnology company, focuses in delivering immunology therapeutics for autoimmune and inflammatory diseases in the United States. The company's products include Rosnilimab, a selective pathogenic T cell deplete which completed a Phase 2b trial for the treatment of moderate-to-severe rheumatoid arthritis; ANB033, a CD122 antagonist, which is in a Phase 1b trial for celiac disease and eosinophilic esophagitis; ANB101, a BDCA2 modulator antibody which is in Phase 1a trial that specifically targets plasmacytoid dendritic cells and inhibits interferon secretion and modulates antigen presentation; dostarlimab, a PD-1 antagonist for various solid tumor indications; and Imsidolimab, an antibody that inhibits the interleukin-36 receptor, which is in the Phase 3 development for the treatment of generalized pustular psoriasis. It focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations. It has collaborations agreement with GSK and Vanda. The company was formerly known as Anaptys Biosciences, Inc. and changed its name to AnaptysBio, Inc. in July 2006. AnaptysBio, Inc. was incorporated in 2005 and is based in San Diego, California.
5-year financial trends. Figures in USD millions.
Latest fiscal year: 2025
Year-by-year revenue, profitability, and cash flow (USD millions, last 10 years)
| Year | Revenue | EBITDA | Net Profit | FCF | ROE | Rev Growth 1Y | NP Growth 1Y |
|---|---|---|---|---|---|---|---|
| 2025 | $235M | $69M | $-13M | $20M | -35.6% | 157.0% | -90.9% |
| 2024 | $91M | $-93M | $-145M | $-136M | -204.9% | 432.0% | -11.2% |
| 2023 | $17M | $-143M | $-164M | $-122M | -185.7% | 66.8% | 27.1% |
| 2022 | $10M | $-105M | $-129M | $-74M | -49.1% | - | - |
| 2021 | - | - |
Income statement, balance sheet, and cash flow as reported
Consolidated Figures in USD Millions.
| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Total Revenue | - | 10.29 | 17.16 | 91.28 | 234.60 |
| Operating Revenue | - | 10.29 | 17.16 | 91.28 | 234.60 |
| Operating Expense | - | 125.44 | 174.23 | 206.23 | 186.71 |
| Research And Development | - | 88.80 | 132.28 | 163.84 | 135.97 |
| Selling General And Administration | - | 36.64 | 41.95 | 42.39 | 50.74 |
| Total Expenses | - | 125.44 | 174.23 | 206.23 | 186.71 |
| Operating Income | - | -115.15 | -157.07 | -114.95 | 47.90 |
| Total Operating Income As Reported | - | -115.15 | -164.41 | -114.95 | 47.90 |
| EBITDA | - | -105.26 | -143.16 | -92.74 | 69.25 |
| Normalized EBITDA | - | -105.26 | -135.82 | -92.74 | 69.25 |
| EBIT | - | -107.59 | -145.54 | -95.14 | 66.82 |
| Interest Income | - | 7.55 | 18.87 | 19.79 | 13.50 |
| Interest Expense | - | 21.11 | 18.08 | 50.09 | 79.89 |
| Net Interest Income | - | -13.56 | 0.79 | -30.29 | -66.39 |
| Other Non Operating Income Expenses | - | 0.01 | 0 | 0.01 | 5.43 |
| Other Income Expense | - | 0.01 | -7.34 | 0.01 | 5.43 |
| Interest Income Non Operating | - | 7.55 | 18.87 | 19.79 | 13.50 |
| Interest Expense Non Operating | - | 21.11 | 18.08 | 50.09 | 79.89 |
| Net Non Operating Interest Income Expense | - | -13.56 | 0.79 | -30.29 | -66.39 |
| Pretax Income | - | -128.70 | -163.62 | -145.23 | -13.07 |
| Tax Provision | - | 0.02 | 0 | 0 | 0.16 |
| Tax Rate For Calcs | - | 0 | 0 | 0 | 0 |
| Tax Effect Of Unusual Items | - | 0 | 0 | 0 | 0 |
| Net Income Continuous Operations | - | -128.72 | -163.62 | -145.23 | -13.23 |
| Net Income From Continuing And Discontinued Operation | - | -128.72 | -163.62 | -145.23 | -13.23 |
| Net Income From Continuing Operation Net Minority Interest | - | -128.72 | -163.62 | -145.23 | -13.23 |
| Net Income | - | -128.72 | -163.62 | -145.23 | -13.23 |
| Net Income Common Stockholders | - | -128.72 | -163.62 | -145.23 | -13.23 |
| Net Income Including Noncontrolling Interests | - | -128.72 | -163.62 | -145.23 | -13.23 |
| Normalized Income | - | -128.72 | -156.28 | -145.23 | -13.23 |
| Diluted NI Availto Com Stockholders | - | -128.72 | -163.62 | -145.23 | -13.23 |
| Basic Average Shares | - | 28.16 | 26.92 | 28.38 | 28.76 |
| Diluted Average Shares | - | 28.16 | 26.92 | 28.38 | 28.76 |
| Reconciled Depreciation | - | 2.34 | 2.38 | 2.40 | 2.42 |
| Total Unusual Items | - | 0 | -7.34 | 0 | 0 |
| Total Unusual Items Excluding Goodwill | - | 0 | -7.34 | 0 | 0 |
| Special Income Charges | - | 0 | -7.34 | 0 | 0 |
| Other Special Charges | - | - | 7.34 | - | - |
| Restructuring And Mergern Acquisition | - | 0 | 7.34 | 0 | 0 |
| General And Administrative Expense | - | 36.64 | 41.95 | 42.39 | 50.74 |
| Other Gand A | - | 36.64 | 41.95 | 42.39 | 50.74 |
Healthcare sector peers, ranked by market cap
| Company | Ticker | Market Cap | P/E | P/B | ROE | EV/EBITDA |
|---|---|---|---|---|---|---|
| AnaptysBio, Inc.this co. | ANAB | $1.5B | - | 40.41 | -35.6% | 17.42 |
| Vir Biotechnology, Inc. | VIR | $1.5B | - | 2.02 | -57.2% | - |
| ArriVent BioPharma, Inc. | AVBP | $1.5B | - | 5.02 | -54.1% | - |
| PROCEPT BioRobotics Corporation | PRCT | $1.5B | -16.08 | 4.20 | -26.1% | -15.56 |
| STAAR Surgical Company | STAA | $1.5B | -18.48 |
| - |
| - |
| - |
| - |
| - |
| 4.32 |
| -23.4% |
| -36.86 |
| Perrigo Company plc | PRGO | $1.5B | -1.04 | 0.50 | -48.6% | -5.75 |
| NeoGenomics, Inc. | NEO | $1.5B | -13.63 | 1.76 | -12.9% | -44.52 |
| MBX Biosciences, Inc. | MBX | $1.5B | -16.92 | 3.98 | -23.6% | -14.28 |
| Monte Rosa Therapeutics, Inc. | GLUE | $1.5B | -37.97 | 6.29 | -16.6% | -30.01 |
| Peer Median | - | -16.50 | 4.09 | -24.8% | -22.78 | |