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Equiscale · Syntellia LLC
ClearPoint Neuro, Inc., a commercial-stage medical device company, focuses on the development and commercialization of platforms for performing minimally invasive surgical procedures in the brain in the United States. The company offers ClearPoint systems, such as ClearPoint hardware, which includes head fixation frame, computer workstation, and in-room monitor; and ClearPoint disposables, which consist of SmartFrame trajectory device, a hand controller and related accessories, and its SmartFlow Neuro cannula. It also provides ClearPoint software, which guides the physician in surgical planning, device alignment, navigation to the target, and procedure monitoring; ClearPoint Prism Neuro laser therapy system to necrotize or coagulate soft tissue; and IRRAflow system, an active fluid exchange platform. In addition, the company offers consulting services to its pharmaceutical and other medical technology partners, such as benchtop testing, preclinical studies, clinical trial support, regulatory consultation, and translation from the preclinical to the clinical setting. It has licenses and collaboration agreements with Koninklijke Philips N.V., UCB Biopharma SRL, Clinical Laserthermia Systems AB, University of California, San Francisco, and NE Scientific, LLC. The company was formerly known as MRI Interventions, Inc. and changed its name to ClearPoint Neuro, Inc. in February 2020. ClearPoint Neuro, Inc. was incorporated in 1998 and is headquartered in Solana Beach, California.
Rule-based from financial data. Not advice.
5-year financial trends. Figures in USD millions.
Latest fiscal year: 2025
Year-by-year revenue, profitability, and cash flow (USD millions, last 10 years)
| Year | Revenue | EBITDA | Net Profit | FCF | ROE | Rev Growth 1Y | NP Growth 1Y |
|---|---|---|---|---|---|---|---|
| 2025 | $37M | $-21M | $-26M | $-24M | -91.1% | 17.8% | 35.0% |
| 2024 | $31M | $-16M | $-19M | $-9M | -74.5% | 31.0% | -14.4% |
| 2023 | $24M | $-21M | $-22M | $-15M | -104.3% | 16.6% | 34.4% |
| 2022 | $21M | $-16M | $-16M | $-17M | -44.6% | - | - |
| 2021 | - |
Income statement, balance sheet, and cash flow as reported
Consolidated Figures in USD Millions.
| Metric | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Total Revenue | - | 20.55 | 23.96 | 31.39 | 36.97 |
| Operating Revenue | - | 20.55 | 23.96 | 31.39 | 36.97 |
| Cost Of Revenue | - | 7.02 | 10.34 | 12.27 | 14.28 |
| Gross Profit | - | 13.53 | 13.61 | 19.12 | 22.69 |
| Operating Expense | - | 29.86 | 36.06 | 38.86 | 46.86 |
| Research And Development | - | 10.89 | 11.71 | 12.39 | 13.90 |
| Selling General And Administration | - | 18.97 | 24.35 | 26.46 | 32.96 |
| Total Expenses | - | 36.88 | 46.40 | 51.12 | 61.14 |
| Operating Income | - | -16.33 | -22.45 | -19.73 | -24.16 |
| Total Operating Income As Reported | - | -16.33 | -22.45 | -19.73 | -24.16 |
| EBITDA | - | -15.58 | -20.99 | -16.48 | -20.86 |
| Normalized EBITDA | - | -15.58 | -20.99 | -16.48 | -20.86 |
| EBIT | - | -16.35 | -22.45 | -18.38 | -23.10 |
| Interest Income | - | - | 0.39 | 1.39 | 1.21 |
| Interest Expense | 0.97 | 0.08 | - | 0.52 | 2.39 |
| Net Interest Income | - | -0.08 | 0.39 | 0.87 | -1.18 |
| Other Non Operating Income Expenses | - | -0.02 | -0.03 | -0.04 | -0.15 |
| Other Income Expense | - | -0.02 | -0.03 | -0.04 | -0.15 |
| Interest Income Non Operating | - | - | 0.39 | 1.39 | 1.21 |
| Interest Expense Non Operating | 0.97 | 0.08 | - | 0.52 | 2.39 |
| Net Non Operating Interest Income Expense | - | -0.08 | 0.39 | 0.87 | -1.18 |
| Pretax Income | - | -16.43 | -22.09 | -18.90 | -25.48 |
| Tax Provision | - | - | - | 0.01 | 0.06 |
| Tax Rate For Calcs | - | 0 | 0 | 0 | 0 |
| Tax Effect Of Unusual Items | - | 0 | 0 | 0 | 0 |
| Net Income Continuous Operations | - | -16.43 | -22.09 | -18.91 | -25.54 |
| Net Income From Continuing And Discontinued Operation | - | -16.43 | -22.09 | -18.91 | -25.54 |
| Net Income From Continuing Operation Net Minority Interest | - | -16.43 | -22.09 | -18.91 | -25.54 |
| Net Income | - | -16.43 | -22.09 | -18.91 | -25.54 |
| Net Income Common Stockholders | - | -16.43 | -22.09 | -18.91 | -25.54 |
| Net Income Including Noncontrolling Interests | - | -16.43 | -22.09 | -18.91 | -25.54 |
| Normalized Income | - | -16.43 | -22.09 | -18.91 | -25.54 |
| Diluted NI Availto Com Stockholders | - | -16.43 | -22.09 | -18.91 | -25.54 |
| Basic Average Shares | 20.73 | 24.18 | 24.61 | 27.03 | - |
| Diluted Average Shares | 20.73 | 24.18 | 24.61 | 27.03 | - |
| Reconciled Depreciation | - | 0.78 | 1.46 | 1.90 | 2.24 |
| Reconciled Cost Of Revenue | - | 7.02 | 10.34 | 12.27 | 14.28 |
| General And Administrative Expense | - | 9.61 | 11.76 | 11.99 | 16.50 |
| Other Gand A | - | 9.61 | 11.76 | 11.99 | 16.50 |
| Selling And Marketing Expense | - | 9.36 | 12.60 | 14.48 | 16.46 |
Healthcare sector peers, ranked by market cap
| Company | Ticker | Market Cap | P/E | P/B | ROE | EV/EBITDA |
|---|---|---|---|---|---|---|
| ClearPoint Neuro, Inc.this co. | CLPT | $429M | -16.81 | 15.33 | -91.1% | -21.18 |
| NRC Health | NRC | $445M | 38.37 | 31.82 | 82.9% | 17.20 |
| Myriad Genetics, Inc. | MYGN | $443M | -1.21 | 1.20 | -99.4% | -1.52 |
| Varex Imaging Corporation | VREX | $441M | - | 0.93 | -14.9% | 973.79 |
| Emergent BioSolutions Inc. | EBS | $435M |
| - |
| - |
| - |
| - |
| - |
| - |
| 8.28 |
| 0.83 |
| 10.1% |
| 3.37 |
| Evolus, Inc. | EOLS | $435M | -8.42 | -18.81 | 223.5% | -23.79 |
| Rezolute, Inc. | RZLT | $434M | -5.84 | 2.68 | -45.9% | -4.28 |
| Neurogene Inc. | NGNE | $434M | -4.81 | 1.64 | -34.1% | -3.91 |
| Orthofix Medical Inc. | OFIX | $418M | -4.53 | 0.93 | -20.5% | 51.78 |
| Peer Median | - | -4.53 | 1.07 | -17.7% | 0.93 | |
Historically, Sep has averaged the highest return (+11.0%); Nov the lowest (-11.4%).
| Year | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | -5.5%Negative MonthJan 2026: -5.48% | -2.8%Negative MonthFeb 2026: -2.78% | -27.6%Negative MonthMar 2026: -27.61% | +22.9%Positive MonthApr 2026: +22.86% | +13.3%Positive MonthMay 2026: +13.33% | +40.8%Positive MonthJun 2026: +40.81% | -16.3%Negative MonthJul 2026: -16.26% | +6.8%*Positive MonthAug 2026: +6.83% | — | — | — | — |
| 2025 | +13.5%Positive MonthJan 2025: +13.52% | -16.8%Negative MonthFeb 2025: -16.84% | -18.1%Negative MonthMar 2025: -18.11% | +21.0%Positive MonthApr 2025: +21.03% | -17.9%Negative MonthMay 2025: -17.93% | +1.1%Neutral MonthJun 2025: +1.10% | -12.9%Negative MonthJul 2025: -12.90% | +0.9%Neutral MonthAug 2025: +0.87% | +107.7%Positive MonthSep 2025: +107.72% | +6.6%Positive MonthOct 2025: +6.56% | -37.7%Negative MonthNov 2025: -37.73% | -5.4%Negative MonthDec 2025: -5.39% |
| 2024 | +2.5%Positive MonthJan 2024: +2.50% | -8.2%Negative MonthFeb 2024: -8.19% | +6.4%Positive MonthMar 2024: +6.42% | -20.1%Negative MonthApr 2024: -20.15% | +0.0%Neutral MonthMay 2024: +0.00% | -0.7%Neutral MonthJun 2024: -0.74% | +32.8%Positive MonthJul 2024: +32.84% | +81.3%Positive MonthAug 2024: +81.28% | -13.6%Negative MonthSep 2024: -13.64% | +10.5%Positive MonthOct 2024: +10.53% | -0.2%Neutral MonthNov 2024: -0.16% | +24.3%Positive MonthDec 2024: +24.33% |
| 2023 | +12.3%Positive MonthJan 2023: +12.28% | -10.8%Negative MonthFeb 2023: -10.83% | -0.5%Neutral MonthMar 2023: -0.47% | +24.6%Positive MonthApr 2023: +24.64% | -26.8%Negative MonthMay 2023: -26.81% | -6.0%Negative MonthJun 2023: -5.97% | -5.1%Negative MonthJul 2023: -5.11% | -15.4%Negative MonthAug 2023: -15.43% | -13.8%Negative MonthSep 2023: -13.77% | +9.8%Positive MonthOct 2023: +9.78% | +4.7%Positive MonthNov 2023: +4.73% | +17.9%Positive MonthDec 2023: +17.88% |
| 2022 | -21.3%Negative MonthJan 2022: -21.30% | -0.9%Neutral MonthFeb 2022: -0.91% | +19.0%Positive MonthMar 2022: +18.97% | -17.7%Negative MonthApr 2022: -17.68% | +27.9%Positive MonthMay 2022: +27.89% | +19.1%Positive MonthJun 2022: +19.07% | +8.6%Positive MonthJul 2022: +8.58% | -9.2%Negative MonthAug 2022: -9.17% | -19.5%Negative MonthSep 2022: -19.50% | -3.4%Negative MonthOct 2022: -3.38% | -5.8%Negative MonthNov 2022: -5.79% | -10.2%Negative MonthDec 2022: -10.18% |
| 2021 | — | — | — | — | -11.6%Negative MonthMay 2021: -11.57% | +3.6%Positive MonthJun 2021: +3.64% | +16.4%Positive MonthJul 2021: +16.45% | -15.1%Negative MonthAug 2021: -15.11% | -5.9%Negative MonthSep 2021: -5.94% | -5.7%Negative MonthOct 2021: -5.75% | -17.9%Negative MonthNov 2021: -17.93% | -18.3%Negative MonthDec 2021: -18.28% |
| Avg±SD |
Each cell is the percentage change in closing price from the end of the prior month to the end of this month. The bottom row shows the average return for that calendar month across the selected years, plus or minus one standard deviation — the range that historically contained roughly two-thirds of outcomes. Past monthly patterns are not a forecast of future returns.
This aggregates every month by calendar position — all Januaries together, all Februaries together, and so on — to show whether a given month has leaned positive or negative historically. ‘Simple’ counts each month as +1 or −1. ‘Weighted’ gives larger moves more influence: +2 above +10%, −2 below −10%. With only 6 years of history for this asset, each month’s score reflects a small number of observations — read it as a historical tendency, not a reliable seasonal pattern.
This tracks a running tally across the asset’s full price history: each month adds or subtracts based on whether it was positive or negative. A rising line means more positive months than negative so far; a flattening or falling line means recent months have leaned negative. This measures historical month-to-month consistency, not expected future performance.
Year-to-date return is calculated by dividing each day’s closing price by the price on January 1st of that year (or the asset’s first available price if it began trading mid-year). The custom average line shows the mean YTD return at each calendar day across the selected years. The standard deviation band shows the range within which returns have historically fallen — at 1 SD, roughly two-thirds of years; at 2 SD, roughly 95%. Past year-to-date patterns do not predict future returns. The average and standard deviation band are computed from the year set chosen in “Average from”, which is independent of which year lines are displayed. The current in-progress year is excluded from these calculations, since a partial year is not comparable to complete ones. Election-cycle groupings follow the US presidential calendar and are offered only for US and crypto assets.
